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Home - Products - GPCR/G Protein - Neurotensin Receptor - SR 142948

SR 142948

CAS No. 184162-64-9

SR 142948( —— )

Catalog No. M23837 CAS No. 184162-64-9

SR 142948 is a neurotensin (NT) receptor antagonist.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    SR 142948
  • Note
    Research use only, not for human use.
  • Brief Description
    SR 142948 is a neurotensin (NT) receptor antagonist.
  • Description
    SR 142948 is a neurotensin (NT) receptor antagonist.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Female Swiss albino CD1 mice (25-30 g; intrastriatal injection of 10 pg/mouse NT).Dosage:2 μg/kg Administration:Oral administration; single.Result:Inhibited the turning behavior with maximal and significant antagonism between 1-2 h after administration.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Neurotensin Receptor
  • Recptor
    Neurotensin Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    184162-64-9
  • Formula Weight
    685.86
  • Molecular Formula
    C39H51N5O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble
  • SMILES
    COc1cccc(OC)c1-c1cc(nn1-c1ccc(cc1C(C)C)C(=O)N(C)CCCN(C)C)C(=O)NC1(C2CC3CC(C2)CC1C3)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.L Quéré, Longfils G , Boigegrain R , et al. X-ray structural characterization of SR 142948, a novel potent synthetic neurotensin receptor antagonist[J]. Bioorganic & Medicinal Chemistry Letters, 1998, 8(6):653-658.
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